Peptide: Difference between revisions
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==Peptides & Backbones== | ==Peptides & Backbones== | ||
This is the <scene name='Peptide~Emartz_view1~2'>backbone</scene> of 1 amino acid. Adding to the backbone with an additional amino acid on each side gives a tripeptide (3 amino acids). No side groups are shown, and most hydrogens are omitted. Now each amino acid has a 1 carbon side group so we have Ala-Ala-Ala (tri-alanine). Adding a carbon chain plus an NH3 on the first amino acid gives Lys-Ala-Ala. Adding three more carbons to the 3rd amino acid gives [[isoleucine]]: Lys-Ala-Ile. The 4th amino acid is threonine with its hydroxyl, giving Lys-Ala-Ile-Thr. Here is the shape of the tetrapeptide (4 AAs). The stick representation has too much detail for larger proteins, so the α-carbons are connected with a line called the backbone trace. Showing only the backbone makes it easier to see the path of the protein chain (its secondary and tertiary structure). | This is the <scene name='Peptide~Emartz_view1~2'>backbone</scene> of 1 amino acid. Adding to the backbone with an additional amino acid on each side gives a <scene name='Peptide~Emartz_view2~1'>tripeptide</scene> (3 amino acids). No side groups are shown, and most hydrogens are omitted. Now each amino acid has a 1 carbon side group so we have <scene name='Peptide~Emartz_view3~1'>Ala-Ala-Ala</scene> (tri-alanine). Adding a carbon chain plus an NH3 on the first amino acid gives <scene name='Peptide~Emartz_view4~1'>Lys-Ala-Ala</scene>. | ||
<scene name='Peptide~Emartz_view5~1'>Adding three more carbons</scene> to the 3rd amino acid gives [[isoleucine]]: Lys-Ala-Ile. The 4th amino acid is threonine with its hydroxyl, giving Lys-Ala-Ile-Thr. Here is the shape of the tetrapeptide (4 AAs). The stick representation has too much detail for larger proteins, so the α-carbons are connected with a line called the backbone trace. Showing only the backbone makes it easier to see the path of the protein chain (its secondary and tertiary structure). | |||
Revision as of 12:29, 11 October 2007
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Peptides are chains of amino acids linked by peptide bonds. Long peptides, or polypeptides, are called proteins.
Peptides & BackbonesPeptides & Backbones
This is the of 1 amino acid. Adding to the backbone with an additional amino acid on each side gives a (3 amino acids). No side groups are shown, and most hydrogens are omitted. Now each amino acid has a 1 carbon side group so we have (tri-alanine). Adding a carbon chain plus an NH3 on the first amino acid gives . to the 3rd amino acid gives isoleucine: Lys-Ala-Ile. The 4th amino acid is threonine with its hydroxyl, giving Lys-Ala-Ile-Thr. Here is the shape of the tetrapeptide (4 AAs). The stick representation has too much detail for larger proteins, so the α-carbons are connected with a line called the backbone trace. Showing only the backbone makes it easier to see the path of the protein chain (its secondary and tertiary structure).