4ht6: Difference between revisions
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{{STRUCTURE_4ht6| PDB=4ht6 | SCENE= }} | |||
===The Structure of a Yeast Dynein Dyn2-Pac11 Complex and Effect on Single Molecule Dynein Motor Activity=== | |||
{{ABSTRACT_PUBMED_23761070}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DYL1_YEAST DYL1_YEAST]] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). [[http://www.uniprot.org/uniprot/PAC11_YEAST PAC11_YEAST]] Required for viability in the absence of the kinesin-related CIN8 mitotic motor. May be a dynein intermediate chain. | |||
==About this Structure== | |||
[[4ht6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HT6 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023761070</ref><references group="xtra"/><references/> | |||
[[Category: Saccharomyces cerevisiae s288c]] | |||
[[Category: Romes, E R.]] | |||
[[Category: Slep, K C.]] | |||
[[Category: Dimerization]] | |||
[[Category: Dynein]] | |||
[[Category: Dynein intermediate chain dynein heavy chain]] | |||
[[Category: Intermediate chain]] | |||
[[Category: Light chain]] | |||
[[Category: Motor protein]] | |||
Revision as of 07:11, 20 September 2013
The Structure of a Yeast Dynein Dyn2-Pac11 Complex and Effect on Single Molecule Dynein Motor ActivityThe Structure of a Yeast Dynein Dyn2-Pac11 Complex and Effect on Single Molecule Dynein Motor Activity
Template:ABSTRACT PUBMED 23761070
FunctionFunction
[DYL1_YEAST] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). [PAC11_YEAST] Required for viability in the absence of the kinesin-related CIN8 mitotic motor. May be a dynein intermediate chain.
About this StructureAbout this Structure
4ht6 is a 6 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Rao L, Romes EM, Nicholas MP, Brenner S, Tripathy A, Gennerich A, Slep KC. The yeast dynein Dyn2-Pac11 complex is a dynein dimerization/processivity factor: structural and single-molecule characterization. Mol Biol Cell. 2013 Aug;24(15):2362-2377. Epub 2013 Jun 12. PMID:23761070 doi:10.1091/mbc.E13-03-0166