4jva: Difference between revisions
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{{STRUCTURE_4jva| PDB=4jva | SCENE= }} | |||
===Crystal Structure of RIIbeta(108-402) bound to HE33, a N6 di-propyl substituted cAMP analog=== | |||
{{ABSTRACT_PUBMED_23978166}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/KAP3_RAT KAP3_RAT]] Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. | |||
==About this Structure== | |||
[[4jva]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JVA OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023978166</ref><references group="xtra"/><references/> | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Brown, S H.J.]] | |||
[[Category: Cheng, C Y.]] | |||
[[Category: Cottam, H.]] | |||
[[Category: Saldanha, A S.]] | |||
[[Category: Sankaran, B.]] | |||
[[Category: Taylor, S S.]] | |||
[[Category: Wu, J.]] | |||
[[Category: Camp-dependent protein kinase]] | |||
[[Category: Cyclic nucleotide analog]] | |||
[[Category: Fluorescence anisotropy]] | |||
[[Category: Isoform selectivity]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 07:11, 20 September 2013
Crystal Structure of RIIbeta(108-402) bound to HE33, a N6 di-propyl substituted cAMP analogCrystal Structure of RIIbeta(108-402) bound to HE33, a N6 di-propyl substituted cAMP analog
Template:ABSTRACT PUBMED 23978166
FunctionFunction
[KAP3_RAT] Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
About this StructureAbout this Structure
4jva is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Brown SH, Cheng CY, Saldanha SA, Wu J, Cottam HB, Sankaran B, Taylor SS. Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs. ACS Chem Biol. 2013 Sep 10. PMID:23978166 doi:10.1021/cb400247t