Sandbox 125: Difference between revisions
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(ii) PY-NLS has an overall positive charge allowing for electrostatic compatibility with Kapβ2. | (ii) PY-NLS has an overall positive charge allowing for electrostatic compatibility with Kapβ2. | ||
(iii) General sequence for the PY-NLS is | (iii) General sequence for the PY-NLS is a hydrophobic basic motif and a R-X2-5-P-Y motif at the C-terminus. | ||
The PY-NLS of 2H4M contains a hydrophobic rather than a basic N-terminal motif. Hydrophobic interactions at the N-terminal motif of the PY-NLS include: | The PY-NLS of 2H4M contains a hydrophobic rather than a basic N-terminal motif. Hydrophobic interactions at the N-terminal motif of the PY-NLS include: | ||