4jfi: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4jfi| PDB=4jfi | SCENE= }} | |||
===Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione=== | |||
{{ABSTRACT_PUBMED_23647266}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN]] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP. | |||
==About this Structure== | |||
[[4jfi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JFI OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023647266</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Peptidylprolyl isomerase]] | |||
[[Category: Bracher, A.]] | |||
[[Category: Fabian, A.]] | |||
[[Category: Gopalakrishnan, R.]] | |||
[[Category: Hausch, F.]] | |||
[[Category: Hoogeland, B.]] | |||
[[Category: Kirschner, A.]] | |||
[[Category: Koch, U.]] | |||
[[Category: Kozany, C.]] | |||
[[Category: Kress, C.]] | |||
[[Category: Wang, Y.]] | |||
[[Category: Fk-506 binding domain]] | |||
[[Category: Hsp90 cochaperone]] | |||
[[Category: Immunophiline]] | |||
[[Category: Isomerase]] | |||
[[Category: Peptidyl-prolyl isomerase]] | |||
Revision as of 10:25, 28 August 2013
Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dioneIncreasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound 1-[(9S,13R,13aR)-1,3-dimethoxy-8-oxo-5,8,9,10,11,12,13,13a-octahydro-6H-9,13-epiminoazocino[2,1-a]isoquinolin-14-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione
Template:ABSTRACT PUBMED 23647266
FunctionFunction
[FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
About this StructureAbout this Structure
4jfi is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Wang Y, Kirschner A, Fabian AK, Gopalakrishnan R, Kress C, Hoogeland B, Koch U, Kozany C, Bracher A, Hausch F. Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control. J Med Chem. 2013 May 23;56(10):3922-35. doi: 10.1021/jm400087k. Epub 2013 May 6. PMID:23647266 doi:10.1021/jm400087k