Sandbox 124: Difference between revisions

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residues in PBP2a; specifically  
residues in PBP2a; specifically  
<scene name='37/372724/Tyr446_and_met641_label/2'>Tyr446 and Met641</scene>.
<scene name='37/372724/Tyr446_and_met641_label/2'>Tyr446 and Met641</scene>.
As a result of ceftobiprole <scene name='37/372724/R2_interaction/4'>tighter binding</scene> to PBP2a as highlighted in green , <scene name='37/372724/Tyr446_and_met641_label/3'>the medicine </scene>, shown as colors of the atom types ([[CPK]]), is able to more efficiently react with the serine active site residue and therefore inhibit the activity of PBP2a.
As a result of ceftobiprole <scene name='37/372724/R2_interaction/4'>tighter binding</scene> to PBP2a as highlighted in green , <scene name='37/372724/Ceftobiprole_in_cpk/1'>the medicine</scene>, shown as colors of the atom types ([[CPK]]), is able to more efficiently react with the serine active site residue and therefore inhibit the activity of PBP2a.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Student, Allison Granberry, Marisa L. VanBrakle