Sandbox 124: Difference between revisions
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residues in PBP2a; specifically | residues in PBP2a; specifically | ||
<scene name='37/372724/Tyr446_and_met641_label/2'>Tyr446 and Met641</scene>. | <scene name='37/372724/Tyr446_and_met641_label/2'>Tyr446 and Met641</scene>. | ||
As a result of its <scene name='37/372724/ | As a result of its <scene name='37/372724/Tyr446_and_met641_label/3'>tighter binding</scene> to PBP2a, ceftobiprole | ||
is able to more efficiently react with the serine active site residue and therefore inhibit the activity of PBP2a. | is able to more efficiently react with the serine active site residue and therefore inhibit the activity of PBP2a. | ||