2jhp: Difference between revisions
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==Overview== | ==Overview== | ||
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series | Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure. | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Bluetongue virus 10 (isolate usa)]] | [[Category: Bluetongue virus 10 (isolate usa)]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Grimes, J | [[Category: Grimes, J M.]] | ||
[[Category: Roy, P.]] | [[Category: Roy, P.]] | ||
[[Category: Stuart, D | [[Category: Stuart, D I.]] | ||
[[Category: Sutton, G.]] | [[Category: Sutton, G.]] | ||
[[Category: GUN]] | [[Category: GUN]] | ||
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[[Category: virion protein]] | [[Category: virion protein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:03:23 2008'' | ||
Revision as of 19:03, 21 February 2008
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THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE
OverviewOverview
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.
About this StructureAbout this Structure
2JHP is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa) with and as ligands. Known structural/functional Site: . Full crystallographic information is available from OCA.
ReferenceReference
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654
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