3vxx: Difference between revisions
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{{STRUCTURE_3vxx| PDB=3vxx | SCENE= }} | {{STRUCTURE_3vxx| PDB=3vxx | SCENE= }} | ||
===Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence=== | ===Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence=== | ||
{{ABSTRACT_PUBMED_23316048}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MBD4_MOUSE MBD4_MOUSE]] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. | |||
==About this Structure== | ==About this Structure== | ||
[[3vxx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VXX OCA]. | [[3vxx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VXX OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023316048</ref><references group="xtra"/><references/> | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Arita, K.]] | [[Category: Arita, K.]] | ||