4jck: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jck|  PDB=4jck  |  SCENE=  }}
===Galectin-3 carbohydrate recognition domain in complex with thioditaloside===
{{ABSTRACT_PUBMED_23864426}}


The entry 4jck is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN]] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref>  


Authors: Bum-Erdene, K., Blanchard, H.
==About this Structure==
[[4jck]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JCK OCA].  


Description: Galectin-3 carbohydrate recognition domain in complex with thioditaloside
==Reference==
<ref group="xtra">PMID:023864426</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Blanchard, H.]]
[[Category: Bum-Erdene, K.]]
[[Category: Beta sandwich]]
[[Category: Carbohydrate binding protein]]
[[Category: Sugar binding protein-inhibitor complex]]

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