4jak: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
{{STRUCTURE_4jak| PDB=4jak | SCENE= }} | |||
===Crystal structure of tRNA (Um34/Cm34) methyltransferase TrmL from Escherichia coli=== | |||
{{ABSTRACT_PUBMED_23804755}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TRML_ECOLI TRML_ECOLI]] Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. Recognition of the target requires a pyridine at position 34 and N(6)-(isopentenyl)-2-methylthioadenosine at position 37.<ref>PMID:20855540</ref> | |||
==About this Structure== | |||
[[4jak]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JAK OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023804755</ref><references group="xtra"/><references/> | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Liu, R J.]] | |||
[[Category: Wang, E D.]] | |||
[[Category: Zhou, M.]] | |||
[[Category: Deep trefoil knot]] | |||
[[Category: Methylation]] | |||
[[Category: Methyltransferase]] | |||
[[Category: Sam binding]] | |||
[[Category: Spout]] | |||
[[Category: Transferase]] | |||
[[Category: Trna modification]] |