4i2h: Difference between revisions
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{{STRUCTURE_4i2h| PDB=4i2h | SCENE= }} | |||
===Ternary complex of mouse TdT with ssDNA and AMPcPP=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. | |||
==About this Structure== | |||
[[4i2h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I2H OCA]. | |||
[[Category: DNA nucleotidylexotransferase]] | |||
[[Category: Mus musculus]] | |||
[[Category: Delarue, M.]] | |||
[[Category: Gouge, J.]] | |||
[[Category: Terminal transferase]] | |||
[[Category: Transferase-dna complex]] |
Revision as of 16:11, 24 July 2013
Ternary complex of mouse TdT with ssDNA and AMPcPPTernary complex of mouse TdT with ssDNA and AMPcPP
FunctionFunction
[TDT_MOUSE] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
About this StructureAbout this Structure
4i2h is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.