4l3i: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
'''Unreleased structure'''
{{STRUCTURE_4l3i|  PDB=4l3i  |  SCENE=  }}
===Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)===


The entry 4l3i is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/PRC1_HUMAN PRC1_HUMAN]] Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle.<ref>PMID:9885575</ref> <ref>PMID:12082078</ref> <ref>PMID:15297875</ref> <ref>PMID:15625105</ref> <ref>PMID:16431929</ref> <ref>PMID:19468300</ref> <ref>PMID:20691902</ref>  


Authors: Subramanian, R., Ti, S., Tan, L., Darst, S.A., Kapoor, T.M.
==About this Structure==
[[4l3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L3I OCA].  


Description: Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Darst, S A.]]
[[Category: Kapoor, T M.]]
[[Category: Subramanian, R.]]
[[Category: Tan, L.]]
[[Category: Ti, S.]]
[[Category: Coiled-coil]]
[[Category: Helical]]
[[Category: Microtubule binding]]
[[Category: Microtubule crosslinking]]
[[Category: Spectrin]]
[[Category: Spindle midzone]]
[[Category: Structural protein]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA