4bvh: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-'''Unreleased structure'''
+{{STRUCTURE_4bvh|  PDB=4bvh  |  SCENE=  }}
+===CRYSTAL STRUCTURE OF HUMAN SIRT3 IN COMPLEX WITH THE INHIBITOR EX-527 AND 2'-O-ACETYL-ADP-RIBOSE===
+{{ABSTRACT_PUBMED_23840057}}
-The entry 4bvh is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/SIR3_HUMAN SIR3_HUMAN]] NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.<ref>PMID:16788062</ref> <ref>PMID:18680753</ref> <ref>PMID:18794531</ref> <ref>PMID:19535340</ref>
-Authors: GERTZ, M., WEYAND, M., STEEGBORN, C.
+==About this Structure==
+[[4bvh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BVH OCA].
-Description: CRYSTAL STRUCTURE OF HUMAN SIRT3 IN COMPLEX WITH THE INHIBITOR EX-527 AND 2'-O-ACETYL-ADP-RIBOSE
+==Reference==
+<ref group="xtra">PMID:023840057</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Gertz, M.]]
+[[Category: Steegborn, C.]]
+[[Category: Weyand, M.]]
+[[Category: Ex-527]]
+[[Category: Hydrolase]]
+[[Category: Inhibitor complex]]