3s8e: Difference between revisions
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{{STRUCTURE_3s8e| PDB=3s8e | SCENE= }} | {{STRUCTURE_3s8e| PDB=3s8e | SCENE= }} | ||
===Phosphorylation regulates assembly of the caspase-6 substrate-binding groove=== | ===Phosphorylation regulates assembly of the caspase-6 substrate-binding groove=== | ||
{{ABSTRACT_PUBMED_22483120}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. | |||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Caspase|Caspase]] | *[[Caspase|Caspase]] | ||
==Reference== | |||
<ref group="xtra">PMID:022483120</ref><references group="xtra"/><references/> | |||
[[Category: Caspase-6]] | [[Category: Caspase-6]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 17:29, 10 July 2013
Phosphorylation regulates assembly of the caspase-6 substrate-binding groovePhosphorylation regulates assembly of the caspase-6 substrate-binding groove
Template:ABSTRACT PUBMED 22483120
FunctionFunction
[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
About this StructureAbout this Structure
3s8e is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Velazquez-Delgado EM, Hardy JA. Phosphorylation regulates assembly of the caspase-6 substrate-binding groove. Structure. 2012 Apr 4;20(4):742-51. Epub 2012 Apr 3. PMID:22483120 doi:10.1016/j.str.2012.02.003