3u3p: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_3u3p|  PDB=3u3p  |  SCENE=  }}
+===The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)===
+{{ABSTRACT_PUBMED_22525750}}
-The entry 3u3p is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/TNR21_HUMAN TNR21_HUMAN]] May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
-Authors: Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
+==About this Structure==
+[[3u3p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U3P OCA].
-Description: The S-SAD phased crystal structure of Death Receptor 6 (DR6) and its solution conformation revealed by SAXS
+==Reference==
+<ref group="xtra">PMID:022525750</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Ding, W.]]
+[[Category: Hung, L W.]]
+[[Category: Jiao, L Y.]]
+[[Category: Liu, Z J.]]
+[[Category: Matsugaki, N.]]
+[[Category: Ru, H.]]
+[[Category: Shaw, N.]]
+[[Category: Wakatsuki, S.]]
+[[Category: Zhang, L G.]]
+[[Category: Zhao, L X.]]
+[[Category: Apoptosis]]
+[[Category: Trigger apoptosis]]