3vkm: Difference between revisions
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{{STRUCTURE_3vkm| PDB=3vkm | SCENE= }} | {{STRUCTURE_3vkm| PDB=3vkm | SCENE= }} | ||
===Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose=== | ===Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose=== | ||
{{ABSTRACT_PUBMED_22913484}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3vkm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VKM OCA]. | [[3vkm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VKM OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:022913484</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Kamitori, S.]] | [[Category: Kamitori, S.]] | ||
Revision as of 15:36, 3 July 2013
Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactoseProtease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose
Template:ABSTRACT PUBMED 22913484
FunctionFunction
[LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.[1]
About this StructureAbout this Structure
3vkm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Yoshida H, Yamashita S, Teraoka M, Itoh A, Nakakita SI, Nishi N, Kamitori S. X-ray Structure of a Protease-resistant Mutant Form of Human Galectin-8 with Two Carbohydrate Recognition Domains. FEBS J. 2012 Aug 22. doi: 10.1111/j.1742-4658.2012.08753.x. PMID:22913484 doi:10.1111/j.1742-4658.2012.08753.x
- ↑ Ideo H, Matsuzaka T, Nonaka T, Seko A, Yamashita K. Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans. J Biol Chem. 2011 Apr 1;286(13):11346-55. Epub 2011 Feb 2. PMID:21288902 doi:10.1074/jbc.M110.195925