4k4z: Difference between revisions
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{{STRUCTURE_4k4z| PDB=4k4z | SCENE= }} | {{STRUCTURE_4k4z| PDB=4k4z | SCENE= }} | ||
===Coxsackievirus B3 polymerase elongation complex (r2_Mg_form)=== | ===Coxsackievirus B3 polymerase elongation complex (r2_Mg_form)=== | ||
{{ABSTRACT_PUBMED_23667424}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4k4z]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_coxsackievirus_b3 Human coxsackievirus b3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4Z OCA]. | [[4k4z]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_coxsackievirus_b3 Human coxsackievirus b3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4Z OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023667424</ref><references group="xtra"/><references/> | |||
[[Category: Human coxsackievirus b3]] | [[Category: Human coxsackievirus b3]] | ||
[[Category: Gong, P.]] | [[Category: Gong, P.]] | ||
Revision as of 14:39, 3 July 2013
Coxsackievirus B3 polymerase elongation complex (r2_Mg_form)Coxsackievirus B3 polymerase elongation complex (r2_Mg_form)
Template:ABSTRACT PUBMED 23667424
FunctionFunction
[Q66338_9ENTO] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS001676_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS001676_004_010047]
About this StructureAbout this Structure
4k4z is a 16 chain structure with sequence from Human coxsackievirus b3. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB. Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. PLoS One. 2013 May 8;8(5):e60272. doi: 10.1371/journal.pone.0060272. Print 2013. PMID:23667424 doi:10.1371/journal.pone.0060272