3roq: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[3roq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROQ OCA]. | [[3roq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ROQ OCA]. | ||
==Reference== | ==Reference== | ||
Revision as of 13:15, 3 July 2013
Crystal structure of human CD38 in complex with compound CZ-46Crystal structure of human CD38 in complex with compound CZ-46
Template:ABSTRACT PUBMED 22142305
FunctionFunction
[CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
About this StructureAbout this Structure
3roq is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Kwong AK, Chen Z, Zhang H, Leung FP, Lam CM, Ting KY, Zhang L, Hao Q, Zhang LH, Lee HC. Catalysis-Based Inhibitors of the Calcium Signaling Function of CD38. Biochemistry. 2011 Dec 14. PMID:22142305 doi:10.1021/bi201509f