4idj: Difference between revisions
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{{STRUCTURE_4idj| PDB=4idj | SCENE= }} | |||
===S.Aureus a-hemolysin monomer in complex with Fab=== | |||
{{ABSTRACT_PUBMED_23416200}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/HLA_STAAU HLA_STAAU]] Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity. | |||
==About this Structure== | |||
[[4idj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IDJ OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023416200</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Staphylococcus aureus]] | |||
[[Category: Strop, P.]] | |||
[[Category: Cytolytic protein]] | |||
[[Category: Fab]] | |||
[[Category: Hemolysin complex with fab]] | |||
[[Category: Immune system]] | |||
[[Category: Secreted]] |