3tt7: Difference between revisions
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{{STRUCTURE_3tt7| PDB=3tt7 | SCENE= }} | {{STRUCTURE_3tt7| PDB=3tt7 | SCENE= }} | ||
===Structure of ClpP from Bacillus subtilis in complex with DFP=== | ===Structure of ClpP from Bacillus subtilis in complex with DFP=== | ||
{{ABSTRACT_PUBMED_22080375}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CLPP_BACSU CLPP_BACSU]] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor.<ref>PMID:16899079</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3tt7]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TT7 OCA]. | [[3tt7]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TT7 OCA]. | ||
== | ==Reference== | ||
<ref group="xtra">PMID:022080375</ref><references group="xtra"/><references/> | |||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Endopeptidase Clp]] | [[Category: Endopeptidase Clp]] | ||
Revision as of 10:33, 30 June 2013
Structure of ClpP from Bacillus subtilis in complex with DFPStructure of ClpP from Bacillus subtilis in complex with DFP
Template:ABSTRACT PUBMED 22080375
FunctionFunction
[CLPP_BACSU] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor.[1]
About this StructureAbout this Structure
3tt7 is a 7 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Lee BG, Kim MK, Song HK. Structural insights into the conformational diversity of ClpP from Bacillus subtilis. Mol Cells. 2011 Nov 9. PMID:22080375 doi:10.1007/s10059-011-0197-1