Pseudouridine synthase: Difference between revisions
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{{STRUCTURE_1k8w| PDB=1k8w | SIZE=400| SCENE= |right|CAPTION=E. coli tRNA pseudouridine synthase complex with stem-loop RNA, pseudouridine monophosphate and sulfate [[1k8w]] }} | {{STRUCTURE_1k8w| PDB=1k8w | SIZE=400| SCENE= |right|CAPTION=E. coli tRNA pseudouridine synthase complex with stem-loop RNA, pseudouridine monophosphate and sulfate [[1k8w]] }} | ||
'''tRNA pseudouridine synthase''' (PUS) catalyzes the conversion of tRNA uridine to tRNA pseudouridine. PUS are active in the ribosomal large subunit (Rlu) and ribosomal small subunit (Rsu). | '''tRNA pseudouridine synthase''' (PUS) catalyzes the conversion of tRNA uridine to tRNA pseudouridine. PUS are active in the ribosomal large subunit (Rlu) and ribosomal small subunit (Rsu). Probable tRNA pseudouridine synthase (PPUS) is a similar enzyme. | ||
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== 3D Structures of tRNA pseudouridine synthase== | == 3D Structures of tRNA pseudouridine synthase== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |||
[[1dj0]] – EcPUS I – ''Escherichia coli''<BR /> | [[1dj0]] – EcPUS I – ''Escherichia coli''<BR /> | ||
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[[3dh3]] - EcPUS RluF + RNA<BR /> | [[3dh3]] - EcPUS RluF + RNA<BR /> | ||
[[2nqp]], [[2nr0]], [[2nre]] – EcPUS TruA + Leu-tRNA<BR /> | [[2nqp]], [[2nr0]], [[2nre]] – EcPUS TruA + Leu-tRNA<BR /> | ||
[[3hjw]], [[3lwo]], [[3lwp]], [[3lwq]], [[3lwr]], [[3lwv]] – PfPUS | [[3hjw]], [[3lwo]], [[3lwp]], [[3lwq]], [[3lwr]], [[3lwv]] – PfPUS Cbf5 + ribosome biogenesis protein Nop10 + ribosomal protein L7 + RNA – ''Pyrococcus furiosus''<BR /> | ||
[[3mqk]] - PfPUS | [[3mqk]] - PfPUS Cbf5 + ribosome biogenesis protein Nop10 + small nuclear RNP Gar1-like protein + RNA<BR /> | ||
[[3hjy]] - PfPUS | [[3hjy]] - PfPUS Cbf5 + ribosome biogenesis protein NOP10 + RNA<BR /> | ||
[[1ze2]] - TmPUS B + RNA<BR /> | [[1ze2]] - TmPUS B + RNA<BR /> | ||
[[2ab4]] - TmPUS B (mutant) + RNA<BR /> | [[2ab4]] - TmPUS B (mutant) + RNA<BR /> | ||
[[1r3e]], [[1r3f]] - EcPUS B + RNA<BR /> | [[1r3e]], [[1r3f]] - EcPUS B + RNA<BR /> | ||
===PPUS=== | |||
[[2apo]] – PPUS + ribosome biogenesis protein Nop10 – ''Methanocaldococcus jannaschii''<br /> | |||
[[2ey4]] - PfPPUS Cbf5 + ribosome biogenesis protein Nop10 + small nucleolar RNP <br /> | |||
[[2hvy]], [[3hax]] - PfPPUS B + ribosome biogenesis protein Nop10 + ribosomal protein L7 + RNA<br /> | |||
[[2rfk]] - PfPUS B + ribosome biogenesis protein Nop10 + small nucleolar RNP + RNA<br /> | |||
[[3hay]] - PfPPUS B + ribosome biogenesis protein Nop10 + ribosomal protein L7 + small nucleolar RNP + RNA<br /> | |||
[[2aus]] – PUS B + ribosome biogenesis protein Nop10 – ''Pyrococcus abyssi'' | [[2aus]] – PUS B + ribosome biogenesis protein Nop10 – ''Pyrococcus abyssi'' | ||