3rv9: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
{{STRUCTURE_3rv9| PDB=3rv9 | SCENE= }} | {{STRUCTURE_3rv9| PDB=3rv9 | SCENE= }} | ||
===Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Ethyl R-Group=== | ===Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Ethyl R-Group=== | ||
{{ABSTRACT_PUBMED_22607697}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MBTI_MYCTU MBTI_MYCTU]] Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicylate-based siderophore mycobactin.<ref>PMID:16923875</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3rv9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RV9 OCA]. | [[3rv9]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RV9 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022607697</ref><references group="xtra"/> | <ref group="xtra">PMID:022607697</ref><references group="xtra"/><references/> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Bulloch, E M.M.]] | [[Category: Bulloch, E M.M.]] |