3vtc: Difference between revisions
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{{STRUCTURE_3vtc| PDB=3vtc | SCENE= }} | |||
===Crystal structure of rat vitamin D receptor bound to a partial agonist 26-adamantyl-23-yne-19-norvitammin D ADTK3=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/VDR_RAT VDR_RAT]] Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.<ref>PMID:17227670</ref> | |||
==About this Structure== | |||
[[3vtc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTC OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Ikura, T.]] | |||
[[Category: Ito, N.]] | |||
[[Category: Kudo, T.]] | |||
[[Category: Makishima, M.]] | |||
[[Category: Nakabayashi, M.]] | |||
[[Category: Tokiwa, H.]] | |||
[[Category: Yamada, S.]] | |||
[[Category: Hormone receptor]] | |||
[[Category: Transcription]] |