4axm: Difference between revisions
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{{STRUCTURE_4axm| PDB=4axm | SCENE= }} | {{STRUCTURE_4axm| PDB=4axm | SCENE= }} | ||
===TRIAZINE CATHEPSIN INHIBITOR COMPLEX=== | ===TRIAZINE CATHEPSIN INHIBITOR COMPLEX=== | ||
{{ABSTRACT_PUBMED_23658062}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4axm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AXM OCA]. | [[4axm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AXM OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023658062</ref><references group="xtra"/><references/> | |||
[[Category: Cathepsin L]] | [[Category: Cathepsin L]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 18:54, 19 June 2013
TRIAZINE CATHEPSIN INHIBITOR COMPLEXTRIAZINE CATHEPSIN INHIBITOR COMPLEX
Template:ABSTRACT PUBMED 23658062
FunctionFunction
[CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.
About this StructureAbout this Structure
4axm is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Ehmke V, Winkler E, Banner DW, Haap W, Schweizer WB, Rottmann M, Kaiser M, Freymond C, Schirmeister T, Diederich F. Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-ray Crystal Structure Analysis with Human Cathepsin L. ChemMedChem. 2013 Jun;8(6):967-75. doi: 10.1002/cmdc.201300112. Epub 2013 May 9. PMID:23658062 doi:10.1002/cmdc.201300112