3w4j: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3w4j|  PDB=3w4j  |  SCENE=  }}
===Crystal Structure of human DAAO in complex with coumpound 12===
{{ABSTRACT_PUBMED_23566269}}


The entry 3w4j is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/OXDA_HUMAN OXDA_HUMAN]] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.<ref>PMID:17303072</ref> 


Authors: Hondo, T., Warizaya, M., Niimi, T., Namatame, I., Yamaguchi, T., Nakanishi, K., Hamajima, T., Harada, K., Sakashita, H., Matsumoto, Y., Orita, M., Watanabe, T., Takeuchi, M.
==About this Structure==
[[3w4j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4J OCA].  


Description: Crystal Structure of human DAAO in complex with coumpound 12
==Reference==
<ref group="xtra">PMID:023566269</ref><references group="xtra"/><references/>
[[Category: D-amino-acid oxidase]]
[[Category: Homo sapiens]]
[[Category: Hamajima, T.]]
[[Category: Harada, K.]]
[[Category: Hondo, T.]]
[[Category: Matsumoto, Y.]]
[[Category: Nakanishi, K.]]
[[Category: Namatame, I.]]
[[Category: Niimi, T.]]
[[Category: Orita, M.]]
[[Category: Sakashita, H.]]
[[Category: Takeuchi, M.]]
[[Category: Warizaya, M.]]
[[Category: Watanabe, T.]]
[[Category: Yamaguchi, T.]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

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