4hj0: Difference between revisions

Revision as of 18:28, 19 June 2013

[GIPR_HUMAN] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

4hj0 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Ravn P, Madhurantakam C, Kunze S, Matthews E, Priest C, O'brien S, Collinson A, Papworth M, Fritsch-Fredin M, Jermutus L, Benthem L, Gruetter M, Jackson RH. Structural and Pharmacological Characterisation of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-Dependent Insulinotropic Polypeptide Receptor. J Biol Chem. 2013 May 20. PMID:23689510 doi:10.1074/jbc.M112.426288

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-'''Unreleased structure'''
+{{STRUCTURE_4hj0|  PDB=4hj0  |  SCENE=  }}
+===Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution===
+{{ABSTRACT_PUBMED_23689510}}
-The entry 4hj0 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/GIPR_HUMAN GIPR_HUMAN]] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
-Authors: Madhurantakam, C., Ravn, P., Gruetter, M.G., Jackson, R.H.
+==About this Structure==
+[[4hj0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ0 OCA].
-Description: Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution
+==Reference==
+<ref group="xtra">PMID:023689510</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Gruetter, M G.]]
+[[Category: Jackson, R H.]]
+[[Category: Madhurantakam, C.]]
+[[Category: Ravn, P.]]
+[[Category: Glucagon receptor sub-family recognition fold]]
+[[Category: Immune system]]