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{{STRUCTURE_3ef1| PDB=3ef1 | SCENE= }} | {{STRUCTURE_3ef1| PDB=3ef1 | SCENE= }} | ||
===The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase=== | ===The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase=== | ||
{{ABSTRACT_PUBMED_19026779}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FCP1_SCHPO FCP1_SCHPO]] Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. | |||
==About this Structure== | ==About this Structure== | ||
[[3ef1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EF1 OCA]. | [[3ef1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EF1 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019026779</ref><references group="xtra"/> | <ref group="xtra">PMID:019026779</ref><references group="xtra"/><references/> | ||
[[Category: Phosphoprotein phosphatase]] | [[Category: Phosphoprotein phosphatase]] | ||
[[Category: Schizosaccharomyces pombe]] | [[Category: Schizosaccharomyces pombe]] | ||
Revision as of 16:22, 19 June 2013
The Structure of Fcp1, an essential RNA polymerase II CTD phosphataseThe Structure of Fcp1, an essential RNA polymerase II CTD phosphatase
Template:ABSTRACT PUBMED 19026779
FunctionFunction
[FCP1_SCHPO] Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II.
About this StructureAbout this Structure
3ef1 is a 1 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Ghosh A, Shuman S, Lima CD. The structure of Fcp1, an essential RNA polymerase II CTD phosphatase. Mol Cell. 2008 Nov 21;32(4):478-90. PMID:19026779 doi:10.1016/j.molcel.2008.09.021