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{{STRUCTURE_3vfl| PDB=3vfl | SCENE= }} | |||
===Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae=== | |||
{{ABSTRACT_PUBMED_20057065}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/A5LD17_STREE A5LD17_STREE]] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA) (By similarity).[HAMAP-Rule:MF_00418][SAAS:SAAS005263_004_011311] | |||
==About this Structure== | |||
[[3vfl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_sp3-bs71 Streptococcus pneumoniae sp3-bs71]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3h5d 3h5d]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VFL OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:020057065</ref><references group="xtra"/><references/> | |||
[[Category: 4-hydroxy-tetrahydrodipicolinate synthase]] | |||
[[Category: Streptococcus pneumoniae sp3-bs71]] | |||
[[Category: Gorman, M A.]] | |||
[[Category: Dihydrodipicolinate synthase]] | |||
[[Category: Lyase]] | |||
[[Category: Lysine biosynthesis]] |
Revision as of 16:18, 19 June 2013
Structure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniaeStructure, Function, Stability and Knockout Phenotype of Dihydrodipicolinate Synthase from Streptococcus pneumoniae
Template:ABSTRACT PUBMED 20057065
FunctionFunction
[A5LD17_STREE] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA) (By similarity).[HAMAP-Rule:MF_00418][SAAS:SAAS005263_004_011311]
About this StructureAbout this Structure
3vfl is a 2 chain structure with sequence from Streptococcus pneumoniae sp3-bs71. This structure supersedes the now removed PDB entry 3h5d. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Sibarani NE, Gorman MA, Dogovski C, Parker MW, Perugini MA. Crystallization of dihydrodipicolinate synthase from a clinical isolate of Streptococcus pneumoniae. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt, 1):32-6. Epub 2009 Dec 25. PMID:20057065 doi:10.1107/S174430910904771X