2gzl: Difference between revisions
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New page: left|200px<br /><applet load="2gzl" size="450" color="white" frame="true" align="right" spinBox="true" caption="2gzl, resolution 2.50Å" /> '''Structure of 2C-meth... |
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[[Image:2gzl.gif|left|200px]]<br /><applet load="2gzl" size=" | [[Image:2gzl.gif|left|200px]]<br /><applet load="2gzl" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2gzl, resolution 2.50Å" /> | caption="2gzl, resolution 2.50Å" /> | ||
'''Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor'''<br /> | '''Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
2GZL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with ZN, 2AA and GPP as [http://en.wikipedia.org/wiki/ligands ligands]. This structure | 2GZL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=2AA:'>2AA</scene> and <scene name='pdbligand=GPP:'>GPP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 2AO4. Active as [http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZL OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Bacher, A.]] | [[Category: Bacher, A.]] | ||
[[Category: Crane, C | [[Category: Crane, C M.]] | ||
[[Category: Diederich, F.]] | [[Category: Diederich, F.]] | ||
[[Category: Hunter, W | [[Category: Hunter, W N.]] | ||
[[Category: Kaiser, J.]] | [[Category: Kaiser, J.]] | ||
[[Category: Lauw, S.]] | [[Category: Lauw, S.]] | ||
[[Category: Ramsden, N | [[Category: Ramsden, N L.]] | ||
[[Category: Rohdich, F.]] | [[Category: Rohdich, F.]] | ||
[[Category: Wolfgang, E.]] | [[Category: Wolfgang, E.]] | ||
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[[Category: lyase]] | [[Category: lyase]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:36:41 2008'' | ||
Revision as of 18:36, 21 February 2008
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Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor
About this StructureAbout this Structure
2GZL is a Single protein structure of sequence from Escherichia coli with , and as ligands. This structure supersedes the now removed PDB entry 2AO4. Active as 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, with EC number 4.6.1.12 Full crystallographic information is available from OCA.
ReferenceReference
Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy., Crane CM, Kaiser J, Ramsden NL, Lauw S, Rohdich F, Eisenreich W, Hunter WN, Bacher A, Diederich F, Angew Chem Int Ed Engl. 2006 Feb 6;45(7):1069-74. PMID:16392111
Page seeded by OCA on Thu Feb 21 17:36:41 2008