3b12: Difference between revisions
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{{STRUCTURE_3b12| PDB=3b12 | SCENE= }} | {{STRUCTURE_3b12| PDB=3b12 | SCENE= }} | ||
===Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate=== | ===Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate=== | ||
{{ABSTRACT_PUBMED_22674735}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DEHA_BURSP DEHA_BURSP]] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has only very low activity towards chloroacetate.[REFERENCE:1]<ref>PMID:19218394</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022674735</ref><references group="xtra"/> | <ref group="xtra">PMID:022674735</ref><references group="xtra"/><references/> | ||
[[Category: Burkholderia sp.]] | [[Category: Burkholderia sp.]] | ||
[[Category: Haloacetate dehalogenase]] | [[Category: Haloacetate dehalogenase]] | ||
Revision as of 12:04, 19 June 2013
Crystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetateCrystal Structure of the Fluoroacetate Dehalogenase D104 mutant from Burkholderia sp. FA1 in complex with fluoroacetate
Template:ABSTRACT PUBMED 22674735
FunctionFunction
[DEHA_BURSP] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has only very low activity towards chloroacetate.[REFERENCE:1][1]
About this StructureAbout this Structure
3b12 is a 2 chain structure with sequence from Burkholderia sp.. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Nakayama T, Kamachi T, Jitsumori K, Omi R, Hirotsu K, Esaki N, Kurihara T, Yoshizawa K. Substrate Specificity of Fluoroacetate Dehalogenase: An Insight from Crystallographic Analysis, Fluorescence Spectroscopy, and Theoretical Computations. Chemistry. 2012 Jun 1. doi: 10.1002/chem.201103369. PMID:22674735 doi:10.1002/chem.201103369
- ↑ Jitsumori K, Omi R, Kurihara T, Kurata A, Mihara H, Miyahara I, Hirotsu K, Esaki N. X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1. J Bacteriol. 2009 Apr;191(8):2630-7. Epub 2009 Feb 13. PMID:19218394 doi:10.1128/JB.01654-08