3q0c: Difference between revisions

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[[Image:3q0c.jpg|left|200px]]
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{{STRUCTURE_3q0c|  PDB=3q0c  |  SCENE=  }}  
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===Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122===
===Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122===
{{ABSTRACT_PUBMED_21245167}}


 
==Function==
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[[http://www.uniprot.org/uniprot/SUVH5_ARATH SUVH5_ARATH]] Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
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{{ABSTRACT_PUBMED_21245167}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:21245167</ref><references group="xtra"/>
<ref group="xtra">PMID:021245167</ref><references group="xtra"/><references/>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
Line 28: Line 16:
[[Category: Patel, D J.]]
[[Category: Patel, D J.]]
[[Category: Simanshu, D K.]]
[[Category: Simanshu, D K.]]
[[Category: 5mc binding protein]]
[[Category: Fully methylated cg]]
[[Category: Fully methylated cg dna duplex]]
[[Category: Sra]]
[[Category: Suvh5]]
[[Category: Transferase-dna complex]]

Revision as of 11:33, 8 May 2013

Template:STRUCTURE 3q0c

Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122

Template:ABSTRACT PUBMED 21245167

FunctionFunction

[SUVH5_ARATH] Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.

About this StructureAbout this Structure

3q0c is a 4 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Rajakumara E, Law JA, Simanshu DK, Voigt P, Johnson LM, Reinberg D, Patel DJ, Jacobsen SE. A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes Dev. 2011 Jan 15;25(2):137-52. PMID:21245167 doi:10.1101/gad.1980311

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OCA
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