3qmh: Difference between revisions
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{{STRUCTURE_3qmh| PDB=3qmh | SCENE= }} | {{STRUCTURE_3qmh| PDB=3qmh | SCENE= }} | ||
===Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1=== | ===Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1=== | ||
{{ABSTRACT_PUBMED_21407193}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CXXC1_HUMAN CXXC1_HUMAN]] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.<ref>PMID:21407193</ref> | |||
==About this Structure== | ==About this Structure== | ||
Line 22: | Line 10: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:021407193</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
Line 33: | Line 21: | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
[[Category: Xu, C.]] | [[Category: Xu, C.]] | ||
[[Category: Dna binding]] | |||
[[Category: Dna binding protein-dna complex]] | |||
[[Category: Sgc]] | |||
[[Category: Structural genomics consortium]] |
Revision as of 11:10, 8 May 2013
Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1
Template:ABSTRACT PUBMED 21407193
FunctionFunction
[CXXC1_HUMAN] Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.[1]
About this StructureAbout this Structure
3qmh is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Xu C, Bian C, Lam R, Dong A, Min J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011 Mar;2:227. PMID:21407193 doi:10.1038/ncomms1237
- ↑ Xu C, Bian C, Lam R, Dong A, Min J. The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain. Nat Commun. 2011 Mar;2:227. PMID:21407193 doi:10.1038/ncomms1237