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{{STRUCTURE_4jn6| PDB=4jn6 | SCENE= }} | |||
===Crystal Structure of the Aldolase-Dehydrogenase Complex from Mycobacterium tuberculosis HRv37=== | |||
{{ABSTRACT_PUBMED_23614353}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/HOA_MYCTU HOA_MYCTU]] Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity). [[http://www.uniprot.org/uniprot/ACDH_MYCTU ACDH_MYCTU]] Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity). | |||
==About this Structure== | |||
[[4jn6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JN6 OCA]. | |||
[[Category: 4-hydroxy-2-oxovalerate aldolase]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Carere, J.]] | |||
[[Category: Kimber, M S.]] | |||
[[Category: McKenna, S E.]] | |||
[[Category: Seah, S Y.K.]] | |||
[[Category: Aldolase-dehydrogenase]] | |||
[[Category: Lyase-oxidoreductase complex]] | |||
[[Category: Rossmann fold]] | |||
[[Category: Tim barrel]] |
Revision as of 10:45, 8 May 2013
Crystal Structure of the Aldolase-Dehydrogenase Complex from Mycobacterium tuberculosis HRv37Crystal Structure of the Aldolase-Dehydrogenase Complex from Mycobacterium tuberculosis HRv37
Template:ABSTRACT PUBMED 23614353
FunctionFunction
[HOA_MYCTU] Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity). [ACDH_MYCTU] Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity).
About this StructureAbout this Structure
4jn6 is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.