2ypp: Difference between revisions

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[[Image:2ypp.jpg|left|200px]]
{{STRUCTURE_2ypp|  PDB=2ypp  |  SCENE=  }}  
{{STRUCTURE_2ypp|  PDB=2ypp  |  SCENE=  }}  
===3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules===
===3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules===
{{ABSTRACT_PUBMED_23274137}}


{{ABSTRACT_PUBMED_23274137}}
==Function==
[[http://www.uniprot.org/uniprot/AROG_MYCTU AROG_MYCTU]] Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate.<ref>PMID:16288916</ref> 


==About this Structure==
==About this Structure==
[[2ypp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPP OCA].  
[[2ypp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPP OCA].  
==Reference==
<references group="xtra"/><references/>
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]

Revision as of 09:47, 8 May 2013

Template:STRUCTURE 2ypp

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules

Template:ABSTRACT PUBMED 23274137

FunctionFunction

[AROG_MYCTU] Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate.[1]

About this StructureAbout this Structure

2ypp is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

ReferenceReference

  1. Webby CJ, Baker HM, Lott JS, Baker EN, Parker EJ. The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes. J Mol Biol. 2005 Dec 9;354(4):927-39. Epub 2005 Oct 21. PMID:16288916 doi:10.1016/j.jmb.2005.09.093

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