3pak: Difference between revisions

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m Protected "3pak" [edit=sysop:move=sysop]
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[[Image:3pak.png|left|200px]]
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{{STRUCTURE_3pak|  PDB=3pak  |  SCENE=  }}  
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===Crystal Structure of Rat Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with Mannose===
===Crystal Structure of Rat Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with Mannose===
{{ABSTRACT_PUBMED_21047777}}


 
==Function==
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[[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.  
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{{ABSTRACT_PUBMED_21047777}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:21047777</ref><references group="xtra"/>
<ref group="xtra">PMID:021047777</ref><references group="xtra"/><references/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Cafarella, T M.]]
[[Category: Cafarella, T M.]]
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[[Category: Shang, F.]]
[[Category: Shang, F.]]
[[Category: Wu, H.]]
[[Category: Wu, H.]]
[[Category: Collectin]]
[[Category: Mannose]]
[[Category: Sugar binding protein]]

Revision as of 11:37, 2 May 2013

Template:STRUCTURE 3pak

Crystal Structure of Rat Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with MannoseCrystal Structure of Rat Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with Mannose

Template:ABSTRACT PUBMED 21047777

FunctionFunction

[SFTPA_RAT] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

About this StructureAbout this Structure

3pak is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Shang F, Rynkiewicz MJ, McCormack FX, Wu H, Cafarella TM, Head JF, Seaton BA. Crystallographic Complexes of Surfactant Protein A and Carbohydrates Reveal Ligand-induced Conformational Change. J Biol Chem. 2011 Jan 7;286(1):757-65. Epub 2010 Nov 3. PMID:21047777 doi:10.1074/jbc.M110.175265

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OCA
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