3ovb: Difference between revisions
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{{STRUCTURE_3ovb| PDB=3ovb | SCENE= }} | {{STRUCTURE_3ovb| PDB=3ovb | SCENE= }} | ||
===How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA=== | ===How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA=== | ||
{{ABSTRACT_PUBMED_21071662}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CCA_ARCFU CCA_ARCFU]] Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<ref>PMID:14592988</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3ovb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OVB OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:021071662</ref><references group="xtra"/><references/> | ||
[[Category: Archaeoglobus fulgidus]] | [[Category: Archaeoglobus fulgidus]] | ||
[[Category: Pan, B C.]] | [[Category: Pan, B C.]] | ||
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[[Category: Transferase-rna complex]] | [[Category: Transferase-rna complex]] | ||
[[Category: Trna]] | [[Category: Trna]] | ||
Revision as of 11:18, 2 May 2013
How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNAHow the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA
Template:ABSTRACT PUBMED 21071662
FunctionFunction
[CCA_ARCFU] Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.[1]
About this StructureAbout this Structure
3ovb is a 4 chain structure with sequence from Archaeoglobus fulgidus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Pan B, Xiong Y, Steitz TA. How the CCA-adding enzyme selects adenine over cytosine at position 76 of tRNA. Science. 2010 Nov 12;330(6006):937-40. PMID:21071662 doi:10.1126/science.1194985
- ↑ Okabe M, Tomita K, Ishitani R, Ishii R, Takeuchi N, Arisaka F, Nureki O, Yokoyama S. Divergent evolutions of trinucleotide polymerization revealed by an archaeal CCA-adding enzyme structure. EMBO J. 2003 Nov 3;22(21):5918-27. PMID:14592988 doi:http://dx.doi.org/10.1093/emboj/cdg563