4f3c: Difference between revisions
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{{STRUCTURE_4f3c| PDB=4f3c | SCENE= }} | |||
===Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/E8NLP5_SALET E8NLP5_SALET]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[HAMAP-Rule:MF_01684] | |||
==About this Structure== | |||
[[4f3c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_choleraesuis_str._scsa50 Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3C OCA]. | |||
[[Category: Adenosylhomocysteine nucleosidase]] | |||
[[Category: Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]] | |||
[[Category: Almo, S C.]] | |||
[[Category: Bonanno, J B.]] | |||
[[Category: Haapalainen, A M.]] | |||
[[Category: Schramm, V L.]] | |||
[[Category: Thomas, K.]] | |||
[[Category: 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase]] | |||
[[Category: Acting on glycosyl bond]] | |||
[[Category: Adenosylhomocysteine nucleosidase activity]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: L-methionine biosynthetic process from s-adenosylmethionine]] | |||
[[Category: L-methionine salvage from methylthioadenosine]] | |||
[[Category: Methylthioadenosine nucleosidase activity]] |
Revision as of 10:49, 2 May 2013
Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-ACrystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A
FunctionFunction
[E8NLP5_SALET] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[HAMAP-Rule:MF_01684]
About this StructureAbout this Structure
4f3c is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50. Full crystallographic information is available from OCA.
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OCACategories:
- Adenosylhomocysteine nucleosidase
- Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50
- Almo, S C.
- Bonanno, J B.
- Haapalainen, A M.
- Schramm, V L.
- Thomas, K.
- 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase
- Acting on glycosyl bond
- Adenosylhomocysteine nucleosidase activity
- Hydrolase-hydrolase inhibitor complex
- L-methionine biosynthetic process from s-adenosylmethionine
- L-methionine salvage from methylthioadenosine
- Methylthioadenosine nucleosidase activity