User:Fadel A. Samatey/FlhBc I: Difference between revisions
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===Flexibility of N-Terminus=== | ===Flexibility of N-Terminus=== | ||
Molecular dynamics simulations suggested that the mutations in 281-285 reduced flexibility of the N-terminal alpha helix, and hence that such flexibility may be important for function. Indeed, 226-267 (the N-terminal helix) is predicted to be intrinsically disordered. The formation of a helix seems likely to be the result of stabilization by crystal contacts mentioned above. | Molecular dynamics simulations suggested that the mutations in 281-285 reduced flexibility of the N-terminal alpha helix, and hence that such flexibility may be important for function. Indeed, 226-267 (the N-terminal helix) is predicted to be intrinsically disordered<ref><img src='Image:3b0z-FlhB-Foldindex.png'</ref>. The formation of a helix seems likely to be the result of stabilization by crystal contacts mentioned above. | ||
</StructureSection> | </StructureSection> | ||
===References and Notes=== | ===References and Notes=== | ||