2fdq: Difference between revisions

Revision as of 18:20, 21 February 2008

crystal structure of ACBP from Armadillo Harderian Gland

OverviewOverview

The X-ray structure of the tetragonal form of apo acyl-CoA-binding protein (ACBP) from the Harderian gland of the South American armadillo Chaetophractus villosus has been solved. ACBP is a carrier for activated long-chain fatty acids and has been associated with many aspects of lipid metabolism. Its secondary structure is highly similar to that of the corresponding form of bovine ACBP and exhibits the unique flattened alpha-helical bundle (up-down-down-up) motif reported for animal, yeast and insect ACBPs. Conformational differences are located in loops and turns, although these structural differences do not suffice to account for features that could be related to the unusual biochemistry and lipid metabolism of the Harderian gland.

About this StructureAbout this Structure

2FDQ is a Single protein structure of sequence from Chaetophractus villosus. Full crystallographic information is available from OCA.

ReferenceReference

Structure of armadillo ACBP: a new member of the acyl-CoA-binding protein family., Costabel MD, Ermacora MR, Santome JA, Alzari PM, Guerin DM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Oct 1;62(Pt, 10):958-61. Epub 2006 Sep 30. PMID:17012783

Page seeded by OCA on Thu Feb 21 17:20:18 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:2fdq.jpg|left|200px]]<br /><applet load="2fdq" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:2fdq.jpg|left|200px]]<br /><applet load="2fdq" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="2fdq, resolution 3.500&Aring;" />
 '''crystal structure of ACBP from Armadillo Harderian Gland'''<br />
 ==Overview==
-The X-ray structure of the tetragonal form of apo acyl-CoA-binding protein, (ACBP) from the Harderian gland of the South American armadillo, Chaetophractus villosus has been solved. ACBP is a carrier for activated, long-chain fatty acids and has been associated with many aspects of lipid, metabolism. Its secondary structure is highly similar to that of the, corresponding form of bovine ACBP and exhibits the unique flattened, alpha-helical bundle (up-down-down-up) motif reported for animal, yeast, and insect ACBPs. Conformational differences are located in loops and, turns, although these structural differences do not suffice to account for, features that could be related to the unusual biochemistry and lipid, metabolism of the Harderian gland.
+The X-ray structure of the tetragonal form of apo acyl-CoA-binding protein (ACBP) from the Harderian gland of the South American armadillo Chaetophractus villosus has been solved. ACBP is a carrier for activated long-chain fatty acids and has been associated with many aspects of lipid metabolism. Its secondary structure is highly similar to that of the corresponding form of bovine ACBP and exhibits the unique flattened alpha-helical bundle (up-down-down-up) motif reported for animal, yeast and insect ACBPs. Conformational differences are located in loops and turns, although these structural differences do not suffice to account for features that could be related to the unusual biochemistry and lipid metabolism of the Harderian gland.
 ==About this Structure==
-FDQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chaetophractus_villosus Chaetophractus villosus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2FDQ OCA].
+FDQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chaetophractus_villosus Chaetophractus villosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDQ OCA].
 ==Reference==
-Structure of armadillo ACBP: a new member of the acyl-CoA-binding protein family., Costabel MD, Ermacora MR, Santome JA, Alzari PM, Guerin DM, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Oct 1;62(Pt, 10):958-61. Epub 2006 Sep 30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17012783 17012783]
+Structure of armadillo ACBP: a new member of the acyl-CoA-binding protein family., Costabel MD, Ermacora MR, Santome JA, Alzari PM, Guerin DM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Oct 1;62(Pt, 10):958-61. Epub 2006 Sep 30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17012783 17012783]
 [[Category: Chaetophractus villosus]]
 [[Category: Single protein]]
-[[Category: Costabel, M.D.]]
+[[Category: Costabel, M D.]]
-[[Category: Guerin, D.M.A.]]
+[[Category: Guerin, D M.A.]]
 [[Category: acbp]]
 [[Category: diazepam binding inhibitor]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:30:15 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:20:18 2008''