3o2d: Difference between revisions
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{{STRUCTURE_3o2d| PDB=3o2d | SCENE= }} | {{STRUCTURE_3o2d| PDB=3o2d | SCENE= }} | ||
===Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody=== | ===Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody=== | ||
{{ABSTRACT_PUBMED_21134642}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. | |||
==About this Structure== | ==About this Structure== | ||
[[3o2d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2D OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:021134642</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
Line 38: | Line 25: | ||
[[Category: Monoclonal antibody]] | [[Category: Monoclonal antibody]] | ||
[[Category: T cell coreceptor]] | [[Category: T cell coreceptor]] | ||
Revision as of 15:02, 24 April 2013
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibodyCrystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
Template:ABSTRACT PUBMED 21134642
FunctionFunction
[CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
About this StructureAbout this Structure
3o2d is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure. 2010 Dec 8;18(12):1632-41. PMID:21134642 doi:10.1016/j.str.2010.09.017