2f8m: Difference between revisions
New page: left|200px<br /><applet load="2f8m" size="350" color="white" frame="true" align="right" spinBox="true" caption="2f8m, resolution 2.087Å" /> '''Ribose 5-phosphate ... |
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==Overview== | ==Overview== | ||
The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms | The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms resolution. The enzyme, which catalyzes the isomerization reaction that interconverts ribose 5-phosphate and ribulose 5-phosphate, is a member of the pentose phosphate pathway. The P. falciparum enzyme belongs to the ribose 5-phosphate isomerase A family, Pfam family PF06562 (DUF1124), and is structurally similar to other members of the family. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
Structure of ribose 5-phosphate isomerase from Plasmodium falciparum., Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA, Acta | Structure of ribose 5-phosphate isomerase from Plasmodium falciparum., Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):427-31. Epub 2006 Apr 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16682767 16682767] | ||
[[Category: Plasmodium falciparum 3d7]] | [[Category: Plasmodium falciparum 3d7]] | ||
[[Category: Ribose-5-phosphate isomerase]] | [[Category: Ribose-5-phosphate isomerase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Holmes, M | [[Category: Holmes, M A.]] | ||
[[Category: Merritt, E | [[Category: Merritt, E A.]] | ||
[[Category: SGPP, Structural | [[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]] | ||
[[Category: PO4]] | [[Category: PO4]] | ||
[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
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[[Category: structural genomics of pathogenic protozoa consortium]] | [[Category: structural genomics of pathogenic protozoa consortium]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:18:51 2008'' | ||
Revision as of 18:18, 21 February 2008
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Ribose 5-phosphate isomerase from Plasmodium falciparum
OverviewOverview
The structure of ribose 5-phosphate isomerase from Plasmodium falciparum, PFE0730c, has been determined by molecular replacement at 2.09 angstroms resolution. The enzyme, which catalyzes the isomerization reaction that interconverts ribose 5-phosphate and ribulose 5-phosphate, is a member of the pentose phosphate pathway. The P. falciparum enzyme belongs to the ribose 5-phosphate isomerase A family, Pfam family PF06562 (DUF1124), and is structurally similar to other members of the family.
About this StructureAbout this Structure
2F8M is a Single protein structure of sequence from Plasmodium falciparum 3d7 with as ligand. Active as Ribose-5-phosphate isomerase, with EC number 5.3.1.6 Full crystallographic information is available from OCA.
ReferenceReference
Structure of ribose 5-phosphate isomerase from Plasmodium falciparum., Holmes MA, Buckner FS, Van Voorhis WC, Verlinde CL, Mehlin C, Boni E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Zucker F, Schoenfeld LW, Earnest TN, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):427-31. Epub 2006 Apr 12. PMID:16682767
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