2y79: Difference between revisions

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[[Image:2y79.png|left|200px]]
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{{STRUCTURE_2y79|  PDB=2y79  |  SCENE=  }}  
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===STRUCTURE OF THE FIRST GAF DOMAIN E87A MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS===
===STRUCTURE OF THE FIRST GAF DOMAIN E87A MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS===
{{ABSTRACT_PUBMED_21536032}}


 
==Function==
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[[http://www.uniprot.org/uniprot/DEVS_MYCTU DEVS_MYCTU]] Member of the two-component regulatory system DevR/DevS (DosR/DosS) involved in onset of the dormancy response. May act as a redox sensor (rather than a direct hypoxia sensor); the normal (aerobic growth) state is the Fe(3+) form, while the reduced (anaerobic growth) Fe(2+) form is probably active for phosphate transfer. It is probably reduced by flavin nucleotides such as FMN and FAD. May be the primary sensor for CO. Donates a phosphate group to DevR (DosR).<ref>PMID:15033981</ref> <ref>PMID:18474359</ref> <ref>PMID:18400743</ref>
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{{ABSTRACT_PUBMED_21536032}}


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:021536032</ref><references group="xtra"/>
<ref group="xtra">PMID:021536032</ref><references group="xtra"/><references/>
[[Category: Histidine kinase]]
[[Category: Histidine kinase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]

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