3nm9: Difference between revisions

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{{Seed}}
[[Image:3nm9.png|left|200px]]
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{{STRUCTURE_3nm9|  PDB=3nm9  |  SCENE=  }}  
{{STRUCTURE_3nm9|  PDB=3nm9  |  SCENE=  }}  
===HMGD(M13A)-DNA complex===
===HMGD(M13A)-DNA complex===
{{ABSTRACT_PUBMED_20800069}}


 
==Function==
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[[http://www.uniprot.org/uniprot/HMGD_DROME HMGD_DROME]] Binds preferentially single-stranded DNA and unwinds double stranded DNA. Prefers sites containing the sequence 5'-ttg-3'. Facilitates DNA bending. Associated with early embryonic chromatin in the absence of histone H1.<ref>PMID:1373803</ref> <ref>PMID:8168480</ref> <ref>PMID:7720717</ref> 
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{{ABSTRACT_PUBMED_20800069}}


==About this Structure==
==About this Structure==
3NM9 is a 16 chains structure with sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NM9 OCA].  
[[3nm9]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NM9 OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:20800069</ref><references group="xtra"/>
<ref group="xtra">PMID:020800069</ref><references group="xtra"/><references/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Churchill, M E.A.]]
[[Category: Churchill, M E.A.]]
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[[Category: Hmg domain]]
[[Category: Hmg domain]]
[[Category: Non-sequence-specific]]
[[Category: Non-sequence-specific]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  8 11:16:31 2010''

Revision as of 14:46, 24 April 2013

Template:STRUCTURE 3nm9

HMGD(M13A)-DNA complexHMGD(M13A)-DNA complex

Template:ABSTRACT PUBMED 20800069

FunctionFunction

[HMGD_DROME] Binds preferentially single-stranded DNA and unwinds double stranded DNA. Prefers sites containing the sequence 5'-ttg-3'. Facilitates DNA bending. Associated with early embryonic chromatin in the absence of histone H1.[1] [2] [3]

About this StructureAbout this Structure

3nm9 is a 16 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. ↑ Churchill ME, Klass J, Zoetewey DL. Structural Analysis of HMGD-DNA Complexes Reveals Influence of Intercalation on Sequence Selectivity and DNA Bending. J Mol Biol. 2010 Aug 25. PMID:20800069 doi:10.1016/j.jmb.2010.08.031
  1. ↑ Wagner CR, Hamana K, Elgin SC. A high-mobility-group protein and its cDNAs from Drosophila melanogaster. Mol Cell Biol. 1992 May;12(5):1915-23. PMID:1373803
  2. ↑ Ner SS, Travers AA. HMG-D, the Drosophila melanogaster homologue of HMG 1 protein, is associated with early embryonic chromatin in the absence of histone H1. EMBO J. 1994 Apr 15;13(8):1817-22. PMID:8168480
  3. ↑ Churchill ME, Jones DN, Glaser T, Hefner H, Searles MA, Travers AA. HMG-D is an architecture-specific protein that preferentially binds to DNA containing the dinucleotide TG. EMBO J. 1995 Mar 15;14(6):1264-75. PMID:7720717

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