3nmh: Difference between revisions
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{{STRUCTURE_3nmh| PDB=3nmh | SCENE= }} | {{STRUCTURE_3nmh| PDB=3nmh | SCENE= }} | ||
===Crystal structure of the abscisic receptor PYL2 in complex with pyrabactin=== | ===Crystal structure of the abscisic receptor PYL2 in complex with pyrabactin=== | ||
{{ABSTRACT_PUBMED_20729862}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3nmh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMH OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020729862</ref><references group="xtra"/><references/> | ||
[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
[[Category: Kovach, A.]] | [[Category: Kovach, A.]] | ||
| Line 42: | Line 29: | ||
[[Category: Pyl2]] | [[Category: Pyl2]] | ||
[[Category: Pyrabactin]] | [[Category: Pyrabactin]] | ||
Revision as of 14:46, 24 April 2013
Crystal structure of the abscisic receptor PYL2 in complex with pyrabactinCrystal structure of the abscisic receptor PYL2 in complex with pyrabactin
Template:ABSTRACT PUBMED 20729862
FunctionFunction
[PYL2_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.[1] [2]
About this StructureAbout this Structure
3nmh is a 3 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Melcher K, Xu Y, Ng LM, Zhou XE, Soon FF, Chinnusamy V, Suino-Powell KM, Kovach A, Tham FS, Cutler SR, Li J, Yong EL, Zhu JK, Xu HE. Identification and mechanism of ABA receptor antagonism. Nat Struct Mol Biol. 2010 Sep;17(9):1102-8. Epub 2010 Aug 22. PMID:20729862 doi:10.1038/nsmb.1887
- ↑ Melcher K, Ng LM, Zhou XE, Soon FF, Xu Y, Suino-Powell KM, Park SY, Weiner JJ, Fujii H, Chinnusamy V, Kovach A, Li J, Wang Y, Li J, Peterson FC, Jensen DR, Yong EL, Volkman BF, Cutler SR, Zhu JK, Xu HE. A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors. Nature. 2009 Dec 3;462(7273):602-8. PMID:19898420 doi:10.1038/nature08613
- ↑ Yin P, Fan H, Hao Q, Yuan X, Wu D, Pang Y, Yan C, Li W, Wang J, Yan N. Structural insights into the mechanism of abscisic acid signaling by PYL proteins. Nat Struct Mol Biol. 2009 Dec;16(12):1230-6. Epub 2009 Nov 5. PMID:19893533 doi:10.1038/nsmb.1730