4ezy: Difference between revisions

Revision as of 23:27, 17 April 2013

Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLILTGCrystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLILTG

FunctionFunction

[DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]

About this StructureAbout this Structure

4ezy is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
+{{STRUCTURE_4ezy|  PDB=4ezy  |  SCENE=  }}
+===Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLILTG===
+{{ABSTRACT_PUBMED_23562829}}
-The entry 4ezy is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
-Authors: Zahn, M., Straeter, N.
+==About this Structure==
+[[4ezy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZY OCA].
-Description: Crystal structure of the substrate binding domain of E.coli DnaK in complex with the synthetic peptide NRLILTG
+[[Category: Escherichia coli k-12]]
+[[Category: Straeter, N.]]
+[[Category: Zahn, M.]]
+[[Category: Chaperone]]
+[[Category: Peptide binding mode]]