4bhb: Difference between revisions

Revision as of 23:23, 17 April 2013

Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASECrystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE

FunctionFunction

[OGT_MYCTU] Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated (By similarity).

About this StructureAbout this Structure

4bhb is a 1 chain structure with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

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OCA

Revision as of 23:23, 17 April 2013 view source OCA (talk \| contribs) Bots, Bureaucrats, Administrators 3,175,590 edits New page: {{STRUCTURE_4bhb\| PDB=4bhb \| SCENE= }} ===Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE=== {{ABSTRACT_PUBMED_23564173}} ==Function== [[http://www...	Revision as of 23:23, 17 April 2013 view source OCA (talk \| contribs) Bots, Bureaucrats, Administrators 3,175,590 edits m Protected "4bhb" [edit=sysop:move=sysop] Newer edit →
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