4irk: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4irk|  PDB=4irk  |  SCENE=  }}
+===Structure of Polymerase-DNA complex===
+{{ABSTRACT_PUBMED_23525461}}
-The entry 4irk is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/DPO4_ECOLI DPO4_ECOLI]] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. Overexpression of polIV results in increased frameshift mutagenesis. It is required for stationary-phase adaptive mutation, which provides the bacterium with flexibility in dealing with environmental stress, enhancing long-term survival and evolutionary fitness. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.<ref>PMID:9391106</ref> <ref>PMID:11080171</ref> <ref>PMID:11463382</ref> <ref>PMID:11751576</ref> <ref>PMID:12060704</ref>
-Authors: Nair, D.T., Sharma, A.
+==About this Structure==
+[[4irk]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRK OCA].
-Description: structure of Polymerase-DNA complex
+==Reference==
+<references group="xtra"/><references/>
+[[Category: DNA-directed DNA polymerase]]
+[[Category: Escherichia coli k-12]]
+[[Category: Nair, D T.]]
+[[Category: Sharma, A.]]
+[[Category: Dna polymerase]]
+[[Category: Transferase-dna complex]]
+[[Category: Y-family]]