3lsx: Difference between revisions

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-[[Image:3lsx.jpg|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_3lsx", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
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 {{STRUCTURE_3lsx|  PDB=3lsx  |  SCENE=  }}
 ===Piracetam bound to the ligand binding domain of GluA3===
+{{ABSTRACT_PUBMED_20163115}}
+==Function==
-<!--
+[[http://www.uniprot.org/uniprot/GRIA3_RAT GRIA3_RAT]] Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate (By similarity).
-The line below this paragraph, {{ABSTRACT_PUBMED_20163115}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 20163115 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_20163115}}
 ==About this Structure==
-[[3lsx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus,_mus_musculus Rattus norvegicus, mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LSX OCA].
+[[3lsx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LSX OCA].
 ==Reference==
-<ref group="xtra">PMID:20163115</ref><references group="xtra"/>
+<ref group="xtra">PMID:020163115</ref><references group="xtra"/><references/>
-[[Category: Rattus norvegicus, mus musculus]]
+[[Category: Rattus norvegicus]]
 [[Category: Ahmed, A H.]]
 [[Category: Oswald, R E.]]
+[[Category: Allosteric modulator]]
+[[Category: Ampa receptor]]
+[[Category: Glua3]]
+[[Category: Glur3]]
+[[Category: Glutamate receptor]]
+[[Category: Neurotransmitter receptor]]
+[[Category: S1s2]]
+[[Category: Transport protein]]