4fl0: Difference between revisions
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{{STRUCTURE_4fl0| PDB=4fl0 | SCENE= }} | {{STRUCTURE_4fl0| PDB=4fl0 | SCENE= }} | ||
===Crystal structure of ALD1 from Arabidopsis thaliana=== | ===Crystal structure of ALD1 from Arabidopsis thaliana=== | ||
{{ABSTRACT_PUBMED_23385743}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ALD1_ARATH ALD1_ARATH]] Aminotransferase involved in local and systemic acquired resistance (SAR) to the bacterial pathogen P.syringae. Required for salicylic acid (SA) and camalexin accumulation upon pathogen infection. Possesses aminotransferase activity in vitro and may generate amino-acid-derived defense signals in vivo. May be involved in ethylene-induced senescence signaling.<ref>PMID:14729919</ref> <ref>PMID:15447647</ref> <ref>PMID:19825557</ref> <ref>PMID:18266921</ref> <ref>PMID:21530897</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[4fl0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FL0 OCA]. | [[4fl0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FL0 OCA]. | ||
==See Also== | |||
*[[Journal:Acta Cryst F:2|Journal:Acta Cryst F:2]] | |||
==Reference== | |||
<ref group="xtra">PMID:023385743</ref><ref group="xtra">PMID:000000000</ref><references group="xtra"/><references/> | |||
[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
[[Category: Albeck, S.]] | [[Category: Albeck, S.]] | ||
Revision as of 15:34, 7 April 2013
Crystal structure of ALD1 from Arabidopsis thalianaCrystal structure of ALD1 from Arabidopsis thaliana
Template:ABSTRACT PUBMED 23385743
FunctionFunction
[ALD1_ARATH] Aminotransferase involved in local and systemic acquired resistance (SAR) to the bacterial pathogen P.syringae. Required for salicylic acid (SA) and camalexin accumulation upon pathogen infection. Possesses aminotransferase activity in vitro and may generate amino-acid-derived defense signals in vivo. May be involved in ethylene-induced senescence signaling.[1] [2] [3] [4] [5]
About this StructureAbout this Structure
4fl0 is a 2 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Sobolev V, Edelman M, Dym O, Unger T, Albeck S, Kirma M, Galili G. Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Feb 1;69(Pt 2):84-9. doi: , 10.1107/S1744309112050270. Epub 2013 Jan 26. PMID:23385743 doi:10.1107/S1744309112050270
- ↑ Steere AN, Byrne SL, Chasteen ND, Smith VC, Macgillivray RT, Mason AB. Evidence that His349 acts as a pH-inducible switch to accelerate receptor-mediated iron release from the C-lobe of human transferrin. J Biol Inorg Chem. 2010 Aug 14. PMID:20711621 doi:10.1007/s00775-010-0694-2 20711621 10.1007/s00775-010-0694-2
- ↑ Song JT, Lu H, Greenberg JT. Divergent roles in Arabidopsis thaliana development and defense of two homologous genes, aberrant growth and death2 and AGD2-LIKE DEFENSE RESPONSE PROTEIN1, encoding novel aminotransferases. Plant Cell. 2004 Feb;16(2):353-66. Epub 2004 Jan 16. PMID:14729919 doi:10.1105/tpc.019372
- ↑ Song JT, Lu H, McDowell JM, Greenberg JT. A key role for ALD1 in activation of local and systemic defenses in Arabidopsis. Plant J. 2004 Oct;40(2):200-12. PMID:15447647 doi:10.1111/j.1365-313X.2004.02200.x
- ↑ Zhang Z, Lenk A, Andersson MX, Gjetting T, Pedersen C, Nielsen ME, Newman MA, Hou BH, Somerville SC, Thordal-Christensen H. A lesion-mimic syntaxin double mutant in Arabidopsis reveals novel complexity of pathogen defense signaling. Mol Plant. 2008 May;1(3):510-27. doi: 10.1093/mp/ssn011. Epub 2008 Apr 15. PMID:19825557 doi:10.1093/mp/ssn011
- ↑ Lee MW, Jelenska J, Greenberg JT. Arabidopsis proteins important for modulating defense responses to Pseudomonas syringae that secrete HopW1-1. Plant J. 2008 May;54(3):452-65. doi: 10.1111/j.1365-313X.2008.03439.x. Epub 2008 , Feb 7. PMID:18266921 doi:10.1111/j.1365-313X.2008.03439.x
- ↑ Nie H, Wu Y, Yao C, Tang D. Suppression of edr2-mediated powdery mildew resistance, cell death and ethylene-induced senescence by mutations in ALD1 in Arabidopsis. J Genet Genomics. 2011 Apr 20;38(4):137-48. doi: 10.1016/j.jgg.2011.03.001. Epub , 2011 Mar 23. PMID:21530897 doi:10.1016/j.jgg.2011.03.001